Dirk Kuyt headed a winner at 85 minutes to a 1-0 win over Sparta Prague in the first house of Kenny Dalglish to start the European tie as Liverpool manager.
Both sides squandered several opportunities in a separate meeting in the Champions League, but the quality of Liverpool was rewarded for the hard work of Kuyt.
David Ngog, Joe Cole and Raul Meireles added almost in front of a sellout 42,949 crowd, also stressed the dynamism of the new collection system introduced Dalglish.
Sparta, by 3,000 noisy fans backed their own, completing a memorable, if less shock contributed, but without as Kuyt finally has benefited from a late corner. He was the only equalizer.
Maurice Edu scored a spectacular goal in the final minute against the Rangers, post, where he will meet PSV Eindhoven, Sporting Lisbon, smashed the competition after a 2-2 draw at the Estádio José Alvalade.
El-Hadji Diouf, said his first goal for the Rangers before the strike of the former Rangers midfielder Pedro Mendes and Yannick Djalo victory seemed assured for the local computer.
Edu, but was dropped in injury time completed the decisive goal in the link, the Rangers won on away goals after the 1-1 first leg had.
Edin Dzeko scored two goals for Manchester City set up a clash with Dynamo Kiev, the Greek with an easy 3-0 win over minnows Aris.
Aris Greek minnows never went hunting once Dzeko has helped to double in the first 12 minutes. Yaya Toure deflected effort has made a third of the city before the end of a meeting with the side of Andriy Shevchenko, the first leg in Ukraine confirmed two weeks.
Villarreal replied with a deficit to defeat Naples and its place in the next round after a thrilling book the return leg at El Madrigal.
Villarreal, the representatives of Spain in the final round after leaving Sevilla, last night, caused some problems in Naples capped an impressive debut with a preview of the 17 th minute as Marek Hamsik.
The goal means Villarreal, having found the first leg 0-0 in Italy would have to score at least twice to avoid falling, but managed only this break in the space of four minutes from time.
Nilmar saw the team level on 42 minutes before finishing the Italian international Giuseppe Rossi is placed outside of time during the first half.
Goals from Simon Rolfes and Michael Ballack Bayer Leverkusen a 2-0 victory won on the night and a 6-0 victory over Metalist Kharkiv in total, because it relaxes the latter 16.
With Leverkusen lead after the first round 4-0, the game was in really BayArena aside the formality and Jupp Heynckes "qualified for the next round with confidence.
PSV Eindhoven advanced after the fight back to back from a halftime deficit with a convincing 3-1 victory over 10-man Lille.
PSV, fought to 2-0 draw in the first inning with two goals, suffered another anxiety when Lille took 22 minutes ahead against the run of play by Pierre-Alain Frau.
However, the giant Dutch responded after the break and tied for Balazs Dzsudzsak moved quickly before the start of Lille with 10 men shortly after the hour, a woman was the second of two quick bookings.
Giuseppe Rossi celebrates after scoring the goal that Villarreal a 2-1 victory over Napoli sent.
PSV did not take long to make the most of his lead man, soon to create two more goals by Marcelo Antonio Jeremain Lens and a clash with Rangers in the next phase.
Zenit St Petersburg was two goals in the draw to go through a 3.1 (4-3 overall) victory over Young Boys in a thrilling second leg.
The visitors led 2-1 in the first game and extended their lead by Ammar Jemal header from close range, Danko Lazovic balance just before the break.
And the turning point, Sergei Semak, Roman Shirokov shown in the second period, put the tie to beat.
Basel took 75 minutes of their tie against Spartak Moscow in the Champions League but failed to make the decisive second before had in the 90 th Act Aiden McGeady won the band really added to the customers.
Once defeated 3-2 at home in the first link, the need to Basel by two goals to win and things started well when Scott Chipperfield net after 15 minutes.
The Swiss team was unable to fashion a second, if not, have come a sense of their Russian opponents on the goals before McGeady deserved 1-1 draw at night and a 4-3 victory to complete the final moments.
Ajax cruised to the next round with a comprehensive 5-0 win over Anderlecht in Amsterdam.
Anderlecht general manager Herman Van Holsbeeck admitted his side's chances of overturning a 3-0 deficit have été''presque''nul leg.
And he had every reason to Miralem Sulejmani two goals in five minutes in the first half to kill the tie.
Braga overcame a first leg deficit to see the jump to 10 men Lech Poznan and progress on Thursday.
Objectives of the first half of Alan Rodrigo and Lima, the Portuguese saw the match with Liverpool.
Demolished Besiktas Dinamo Kiev for the second time in a week at home in a clash with Manchester City.
Besiktas tried a fight, but spend the time with goals from Ognjen Vukovic, Andriy Yarmolenko, Oleg Gusev and Andriy Shevchenko in the home team claimed a total shock 8-1 victory at Manchester City as a whole.
Eredivisie FC Twente, crowned by a storm in early Rubin Kazan with a 2-2 draw at Arke Stadium seal.
After a 2-0 win in the first leg in Russia, were Michel Preud'homme Bookmark this page with Cristian Ansaldi and progress Cristian Noboa, twice at intervals of three minutes, a possible change of trend.
But Twente coordinated the efforts of the enemies in front of goal and Theo Janssen and Douglas scored on either side of half time music in a 4-2 tie in the victory total.
Paris Saint-Germain made no progress in the goals after the best BATE Barisov.
Header at 89 minutes Peguy Luyindula PSG won 2-2 draw in Belarus last week and ultimately as important as the two sides fought a goalless draw in the French capital.
Goals from Eduardo Salvio and Oscar Cardozo, Benfica travel to Stuttgart 2-0 in the night and 4-1 on the set.
Stuttgart seeks to overthrow a 2-1 deficit, but it was the Portuguese by Salvio instead of just half an hour.
Benfica went on, some of its achievements in Cardozo scored in the 78 minutes.
